SPHERA FUNDS MANAGEMENT LTD.
TEL AVIV L3 · SEC CIK 0001496201
$6.30亿2026Q1 申报市值
96持仓数
36.7%前十大占比 · 第一大 5.8%
17 / 23新建仓 / 清仓
26Q126Q2
前十大持仓 占组合比例
2026Q1 买入最多 按季末市值估算
MLYS 加仓+$2,413.63万
AZN 新建仓+$1,233.22万
RARE 加仓+$1,065.75万
BBIO 加仓+$1,021.08万
PANW 新建仓+$846.49万
2026Q1 卖出最多 按季末市值估算
NICE 重新持有-$1,673.63万
AZN 清仓-$1,241.61万
SEDG 减仓-$733.59万
ANNX 清仓-$660.74万
ORIC 减仓-$591.37万
2026Q1 持仓明细 点表头排序 · 每页 100 行
导出 CSV 🔒| 代码 | 名称 | 市值 ▼ | 占比 | 股数 | 变动股数 | 变动 | 估算买卖额 | 操作 |
|---|---|---|---|---|---|---|---|---|
| MLYS | MINERALYS THERAPEUTICS INC | $3,629.98万 | 5.76% | 1,339,971 | 890,968 | 198.4% | $2,413.63万 | 加仓 |
| — | TEVA PHARMACEUTICAL INDS LTD | $3,424.57万 | 5.44% | 1,136,975 | 13,450 | 1.2% | $40.51万 | 加仓 |
| TSEM | TOWER SEMICONDUCTOR LTD | $2,557.36万 | 4.06% | 145,735 | 23,222 | 19.0% | $407.50万 | 加仓 |
| XBI | SPDR SERIES TRUST 看跌期权 | $2,554.60万 | 4.06% | 200,000 | 130,000 | 185.7% | $1,660.49万 | 加仓 |
| NVMI | NOVA LTD | $2,317.58万 | 3.68% | 53,366 | 5,520 | 11.5% | $239.72万 | 加仓 |
| BBIO | BRIDGEBIO PHARMA INC | $1,821.20万 | 2.89% | 245,246 | 137,500 | 127.6% | $1,021.08万 | 加仓 |
| CYTK | CYTOKINETICS INC 看涨期权 | $1,709.05万 | 2.71% | 259,300 | 259,300 | — | $1,709.05万 | 新建仓 |
| BIIB | BIOGEN INC | $1,696.28万 | 2.69% | 92,526 | -2,212 | -2.3% | -$40.55万 | 减仓 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | $1,695.55万 | 2.69% | 809,333 | 508,710 | 169.2% | $1,065.75万 | 加仓 |
| SNDX | SYNDAX PHARMACEUTICALS INC | $1,692.58万 | 2.69% | 724,563 | -38,000 | -5.0% | -$88.77万 | 减仓 |
| COGT | COGENT BIOSCIENCES INC | $1,602.49万 | 2.54% | 416,340 | 37,840 | 10.0% | $145.65万 | 加仓 |
| SNY | SANOFI SA | $1,298.52万 | 2.06% | 269,515 | 30,000 | 12.5% | $144.54万 | 加仓 |
| AZN | ASTRAZENECA PLC | $1,233.22万 | 1.96% | 62,530 | 62,530 | — | $1,233.22万 | 新建仓 |
| — | AMICUS THERAPEUTIC | $872.48万 | 1.39% | 603,377 | -55,000 | -8.4% | -$79.53万 | 减仓 |
| CLBT | CELLEBRITE DI LTD | $870.24万 | 1.38% | 631,521 | 332,573 | 111.2% | $458.29万 | 重新持有 |
| — | APELLIS PHARMACEUTICALS INC | $864.60万 | 1.37% | 214,914 | -36,047 | -14.4% | -$145.02万 | 减仓 |
| PANW | PALO ALTO NETWORKS INC | $846.49万 | 1.34% | 52,800 | 52,800 | — | $846.49万 | 新建仓 |
| LLY | ELI LILLY & CO | $831.47万 | 1.32% | 9,040 | 0 | 0.0% | — | 不变 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | $824.87万 | 1.31% | 866,464 | 28,575 | 3.4% | $27.20万 | 加仓 |
| CAMT | CAMTEK LTD | $803.84万 | 1.28% | 53,020 | 13,522 | 34.2% | $205.01万 | 加仓 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | $790.30万 | 1.26% | 139,900 | -7,100 | -4.8% | -$40.11万 | 减仓 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | $772.62万 | 1.23% | 243,575 | 3,811 | 1.6% | $12.09万 | 加仓 |
| ORA | ORMAT TECHNOLOGIES INC | $763.85万 | 1.21% | 68,250 | 39,250 | 135.3% | $439.29万 | 重新持有 |
| XENE | XENON PHARMACEUTICALS INC | $738.50万 | 1.17% | 127,000 | 127,000 | — | $738.50万 | 新建仓 |
| — | SOLENO THERAPEUTICS INC | $724.11万 | 1.15% | 216,281 | 79,967 | 58.7% | $267.73万 | 加仓 |
| TNGX | TANGO THERAPEUTICS INC | $718.73万 | 1.14% | 343,563 | -201,000 | -36.9% | -$420.49万 | 减仓 |
| JNJ | JOHNSON & JOHNSON | $704.75万 | 1.12% | 28,831 | -7,000 | -19.5% | -$171.11万 | 减仓 |
| SEDG | SOLAREDGE TECHNOLOGIES INC | $690.96万 | 1.10% | 4,000,000 | 0 | 0.0% | — | 不变 |
| IMTX | IMMATICS N.V | $684.97万 | 1.09% | 696,105 | -165,000 | -19.2% | -$162.36万 | 减仓 |
| TRVI | TREVI THERAPEUTICS INC | $684.82万 | 1.09% | 574,029 | -24,505 | -4.1% | -$29.23万 | 减仓 |
| ORIC | ORIC PHARMACEUTICALS INC | $681.17万 | 1.08% | 537,628 | -466,750 | -46.5% | -$591.37万 | 减仓 |
| MAZE | MAZE THERAPEUTICS INC | $678.62万 | 1.08% | 227,343 | 155,500 | 216.4% | $464.17万 | 加仓 |
| GSK | GSK PLC | $673.32万 | 1.07% | 122,000 | 0 | 0.0% | — | 不变 |
| AMZN | AMAZON COM INC | $665.21万 | 1.06% | 31,940 | 18,180 | 132.1% | $378.63万 | 重新持有 |
| ABBV | ABBVIE INC | $658.04万 | 1.05% | 30,256 | 5,000 | 19.8% | $108.74万 | 加仓 |
| AAOI | APPLIED OPTOELECTRONICS INC | $620.89万 | 0.99% | 73,400 | 73,400 | — | $620.89万 | 新建仓 |
| ELVN | ENLIVEN THERAPEUTICS INC | $600.80万 | 0.95% | 153,265 | -73,500 | -32.4% | -$288.12万 | 减仓 |
| MRK | MERCK & CO INC | $584.61万 | 0.93% | 48,600 | 0 | 0.0% | — | 不变 |
| VOR | VOR BIOPHARMA INC | $574.30万 | 0.91% | 321,917 | -88,500 | -21.6% | -$157.88万 | 减仓 |
| ACAD | ACADIA PHARMACEUTICALS INC | $570.31万 | 0.91% | 256,202 | 44,000 | 20.7% | $97.94万 | 加仓 |
| NVS | NOVARTIS AG | $565.17万 | 0.90% | 37,000 | 0 | 0.0% | — | 不变 |
| ELDN | ELEDON PHARMACEUTICALS INC | $545.82万 | 0.87% | 1,772,131 | -360,000 | -16.9% | -$110.88万 | 减仓 |
| ENPH | ENPHASE ENERGY INC | $538.49万 | 0.86% | 142,419 | -44,081 | -23.6% | -$166.67万 | 减仓 |
| RVMD | REVOLUTION MEDICINES INC | $535.94万 | 0.85% | 55,110 | 2,610 | 5.0% | $25.38万 | 加仓 |
| PFE | PFIZER INC | $522.29万 | 0.83% | 186,000 | 100,000 | 116.3% | $280.80万 | 加仓 |
| BHVN | BIOHAVEN LTD | $502.52万 | 0.80% | 594,000 | 502,845 | 551.6% | $425.41万 | 重新持有 |
| — | FORTE BIOSCIENCES INC | $479.11万 | 0.76% | 184,984 | -885 | -0.5% | -$2.29万 | 减仓 |
| — | CYBIN INC | $473.80万 | 0.75% | 987,090 | 161,514 | 19.6% | $77.53万 | 加仓 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | $473.22万 | 0.75% | 9,040 | 5,740 | 173.9% | $300.47万 | 加仓 |
| SRRK | SCHOLAR ROCK HLDG CORP | $463.41万 | 0.74% | 94,265 | -64,000 | -40.4% | -$314.62万 | 减仓 |
| NVO | NOVO-NORDISK A S | $443.49万 | 0.70% | 120,677 | 5,000 | 4.3% | $18.38万 | 加仓 |
| — | MEDIWOUND LTD | $440.11万 | 0.70% | 273,192 | 42,845 | 18.6% | $69.02万 | 加仓 |
| KOD | KODIAK SCIENCES INC | $437.60万 | 0.69% | 114,796 | -60,704 | -34.6% | -$231.40万 | 减仓 |
| ZBIO | ZENAS BIOPHARMA INC | $419.02万 | 0.67% | 214,334 | 214,334 | — | $419.02万 | 新建仓 |
| — | PROMIS NEUROSCIENCES INC | $413.50万 | 0.66% | 325,591 | 313,784 | 2,657.6% | $398.51万 | 加仓 |
| TLT | ISHARES TR 看涨期权 | $407.44万 | 0.65% | 47,000 | 0 | 0.0% | — | 不变 |
| RLAY | RELAY THERAPEUTICS INC | $406.39万 | 0.65% | 408,436 | 408,436 | — | $406.39万 | 新建仓 |
| SVRA | SAVARA INC | $403.58万 | 0.64% | 739,164 | -439,000 | -37.3% | -$239.69万 | 减仓 |
| WVE | WAVE LIFE SCIENCES LTD | $397.50万 | 0.63% | 548,272 | 140,106 | 34.3% | $101.58万 | 加仓 |
| CRVS | CORVUS PHARMACEUTICALS INC | $362.77万 | 0.58% | 247,961 | -159,748 | -39.2% | -$233.71万 | 减仓 |
| OVID | OVID THERAPEUTICS INC | $360.27万 | 0.57% | 1,622,828 | 1,622,828 | — | $360.27万 | 新建仓 |
| IRON | DISC MEDICINE INC | $342.32万 | 0.54% | 53,538 | 53,538 | — | $342.32万 | 新建仓 |
| UPB | UPSTREAM BIO INC | $322.20万 | 0.51% | 358,000 | 358,000 | — | $322.20万 | 新建仓 |
| — | ALPHA COGNITION INC | $311.62万 | 0.49% | 567,616 | 0 | 0.0% | — | 不变 |
| PALI | PALISADE BIO INC | $303.36万 | 0.48% | 1,733,471 | 1,549,371 | 841.6% | $271.14万 | 加仓 |
| DYN | DYNE THERAPEUTICS INC | $291.16万 | 0.46% | 160,594 | -232,300 | -59.1% | -$421.16万 | 减仓 |
| CLYM | CLIMB BIO INC | $287.18万 | 0.46% | 419,247 | -513,000 | -55.0% | -$351.41万 | 减仓 |
| ZIM | ZIM INTEGRATED SHIPPING SERV | $279.18万 | 0.44% | 105,950 | -30,055 | -22.1% | -$79.19万 | 减仓 |
| — | SATELLOS BIOSCIENCE INC | $275.42万 | 0.44% | 489,207 | 489,207 | — | $275.42万 | 新建仓 |
| SEDG | SOLAREDGE TECHNOLOGIES INC | $269.73万 | 0.43% | 52,836 | -143,700 | -73.1% | -$733.59万 | 减仓 |
| AMGN | AMGEN INC | $263.89万 | 0.42% | 7,500 | 0 | 0.0% | — | 不变 |
| CYTK | CYTOKINETICS INC | $262.43万 | 0.42% | 39,817 | -51,900 | -56.6% | -$342.07万 | 减仓 |
| GPCR | STRUCTURE THERAPEUTICS INC | $244.86万 | 0.39% | 50,800 | 9,800 | 23.9% | $47.24万 | 加仓 |
| KURA | KURA ONCOLOGY INC | $240.26万 | 0.38% | 295,522 | 0 | 0.0% | — | 不变 |
| GENB | GENERATE BIOMEDICINES INC | $231.25万 | 0.37% | 185,000 | 185,000 | — | $231.25万 | 新建仓 |
| IBIT | ISHARES BITCOIN TRUST ETF | $228.62万 | 0.36% | 59,505 | 29,450 | 98.0% | $113.15万 | 加仓 |
| CTNM | CONTINEUM THERAPEUTICS INC | $226.56万 | 0.36% | 173,475 | 0 | 0.0% | — | 不变 |
| TENX | TENAX THERAPEUTICS INC | $217.49万 | 0.35% | 136,015 | -54,096 | -28.5% | -$86.50万 | 减仓 |
| PRLD | PRELUDE THERAPEUTICS INC | $190.95万 | 0.30% | 558,339 | 435,587 | 354.9% | $148.97万 | 加仓 |
| ASND | ASCENDIS PHARMA A/S | $182.98万 | 0.29% | 8,000 | -3,000 | -27.3% | -$68.62万 | 减仓 |
| VSTM | VERASTEM INC | $182.15万 | 0.29% | 343,678 | 0 | 0.0% | — | 不变 |
| — | VOYAGER THERAPEUTICS INC | $181.33万 | 0.29% | 469,761 | 130,000 | 38.3% | $50.18万 | 加仓 |
| STTK | SHATTUCK LABS INC | $180.55万 | 0.29% | 280,786 | 85,574 | 43.8% | $55.02万 | 加仓 |
| EVMN | EVOMMUNE INC | $179.86万 | 0.29% | 78,234 | -87,913 | -52.9% | -$202.11万 | 减仓 |
| BIOA | BIOAGE LABS INC | $151.32万 | 0.24% | 86,518 | -156,517 | -64.4% | -$273.75万 | 减仓 |
| OLMA | OLEMA PHARMACEUTICALS INC 看涨期权 | $149.10万 | 0.24% | 100,000 | 100,000 | — | $149.10万 | 新建仓 |
| ORGO | ORGANOGENESIS HLDGS INC | $130.35万 | 0.21% | 550,000 | 550,000 | — | $130.35万 | 新建仓 |
| — | CURIS INC | $109.18万 | 0.17% | 1,994,937 | 1,994,937 | — | $109.18万 | 新建仓 |
| BMY | BRISTOL-MYERS SQUIBB CO | $106.14万 | 0.17% | 17,500 | 0 | 0.0% | — | 不变 |
| CTMX | CYTOMX THERAPEUTICS INC. | $103.40万 | 0.16% | 220,000 | 220,000 | — | $103.40万 | 新建仓 |
| NICE | NICE LTD | $61.87万 | 0.10% | 5,611 | -151,789 | -96.4% | -$1,673.63万 | 重新持有 |
| — | WEREWOLF THERAPEUTICS INC | $52.19万 | 0.08% | 626,810 | 0 | 0.0% | — | 不变 |
| — | SKYE BIOSCIENCE INC | $41.73万 | 0.07% | 678,928 | 200,000 | 41.8% | $12.29万 | 加仓 |
| DTIL | PRECISION BIOSCIENCES INC | $22.00万 | 0.03% | 40,000 | -356,116 | -89.9% | -$195.86万 | 减仓 |
| — | APREA THERAPEUTICS INC | $20.60万 | 0.03% | 270,000 | 0 | 0.0% | — | 不变 |
| FHTX | FOGHORN THERAPEUTICS INC | $5.84万 | 0.01% | 12,224 | 12,224 | — | $5.84万 | 新建仓 |
| AZN | ASTRAZENECA PLC | $0 | 0.00% | 0 | -67,530 | -100.0% | -$1,241.61万 | 清仓 |
| PRAX | PRAXIS PRECISION MEDICINES I 看涨期权 | $0 | 0.00% | 0 | — | — | — | 申报中断 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN 看涨期权 | $0 | 0.00% | 0 | -350,000 | -100.0% | -$805.00万 | 清仓 |
| ANNX | ANNEXON INC | $0 | 0.00% | 0 | -1,316,212 | -100.0% | -$660.74万 | 清仓 |